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Tamm-Horsfall Protein Regulates Circulating and Renal Cytokines by Affecting Glomerular Filtration Rate and Acting as a Urinary Cytokine Trap

Although few organ systems play a more important role than the kidneys in cytokine catabolism, the mechanism(s) regulating this pivotal physiological function and how its deficiency affects systemic cytokine homeostasis remain unclear. Here we show that elimination of Tamm-Horsfall protein (THP) exp...

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Bibliografiske detaljer
Main Authors: Liu, Yan, El-Achkar, Tarek M., Wu, Xue-Ru
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3351356/
https://ncbi.nlm.nih.gov/pubmed/22451664
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.348243
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