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Molecular and Cellular Effects of Tamm-Horsfall Protein Mutations and Their Rescue by Chemical Chaperones

Correct folding of a nascent polypeptide in the lumen of the endoplasmic reticulum (ER) into a three-dimensional conformation is a crucial step in the stability, intracellular trafficking, and targeting to the final destination of a protein. By transiently and stably expressing human-relevant mutant...

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Bibliografiska uppgifter
Huvudupphovsmän: Ma, Lijie, Liu, Yan, El-Achkar, Tarek M., Wu, Xue-Ru
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Biochemistry and Molecular Biology 2012
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3256885/
https://ncbi.nlm.nih.gov/pubmed/22117067
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.283036
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