Signals in APOBEC3F N-terminal and C-terminal Deaminase Domains Each Contribute to Encapsidation in HIV-1 Virions and Are Both Required for HIV-1 Restriction

Human cytidine deaminases APOBEC3F (A3F) and APOBEC3G (A3G) inhibit human immunodeficiency virus type-1 (HIV-1) replication. In the absence of HIV-1 Vif, A3F and/or A3G are incorporated into assembling virions and exert antiviral functions in subsequently infected target cells. Encapsidation of A3F...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Song, Chisu, Sutton, Lorraine, Johnson, Megan E., D'Aquila, Richard T., Donahue, John P.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Biochemistry and Molecular Biology 2012
Gaiak:
Molecular Bases of Disease
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3351310/
https://ncbi.nlm.nih.gov/pubmed/22451677
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.310839
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