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Nonsteroidal Anti-inflammatory Drugs Alter the Spatiotemporal Organization of Ras Proteins on the Plasma Membrane

Ras proteins on the inner leaflet of the plasma membrane signal from transient nanoscale proteolipid assemblies called nanoclusters. Interactions between the Ras lipid anchors and plasma membrane phospholipids, cholesterol, and actin cytoskeleton contribute to the formation, stability, and dynamics...

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Detalhes bibliográficos
Main Authors: Zhou, Yong, Cho, Kwang-Jin, Plowman, Sarah J., Hancock, John F.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3351306/
https://ncbi.nlm.nih.gov/pubmed/22433858
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.348490
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