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Aphidicolin resistance in herpes simplex virus type I reveals features of the DNA polymerase dNTP binding site.
We describe the mapping and sequencing of mutations within the DNA polymerase gene of herpes simplex virus type 1 which confer resistance to aphidicolin, a DNA polymerase inhibitor. The mutations occur near two regions which are highly conserved among DNA polymerases related to the herpes simplex en...
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| Główni autorzy: | , , , , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
1989
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| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC335127/ https://ncbi.nlm.nih.gov/pubmed/2555788 |
| Etykiety: |
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