Aphidicolin resistance in herpes simplex virus type I reveals features of the DNA polymerase dNTP binding site.

We describe the mapping and sequencing of mutations within the DNA polymerase gene of herpes simplex virus type 1 which confer resistance to aphidicolin, a DNA polymerase inhibitor. The mutations occur near two regions which are highly conserved among DNA polymerases related to the herpes simplex en...

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Podrobná bibliografie

Vydáno v:	Nucleic Acids Res
Hlavní autoři:	Hall, J D, Wang, Y S, Pierpont, J, Berlin, M S, Rundlett, S E, Woodward, S
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Oxford University Press 1989
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC335127/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2555788/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/17.22.9231
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