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Aphidicolin resistance in herpes simplex virus type I reveals features of the DNA polymerase dNTP binding site.
We describe the mapping and sequencing of mutations within the DNA polymerase gene of herpes simplex virus type 1 which confer resistance to aphidicolin, a DNA polymerase inhibitor. The mutations occur near two regions which are highly conserved among DNA polymerases related to the herpes simplex en...
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| Gepubliceerd in: | Nucleic Acids Res |
|---|---|
| Hoofdauteurs: | , , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
Oxford University Press
1989
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| Online toegang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC335127/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2555788/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/17.22.9231 |
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