cn.MOPS: mixture of Poissons for discovering copy number variations in next-generation sequencing data with a low false discovery rate

Quantitative analyses of next-generation sequencing (NGS) data, such as the detection of copy number variations (CNVs), remain challenging. Current methods detect CNVs as changes in the depth of coverage along chromosomes. Technological or genomic variations in the depth of coverage thus lead to a h...

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Bibliografiske detaljer
Main Authors: Klambauer, Günter, Schwarzbauer, Karin, Mayr, Andreas, Clevert, Djork-Arné, Mitterecker, Andreas, Bodenhofer, Ulrich, Hochreiter, Sepp
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2012
Fag:
Methods Online
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3351174/
https://ncbi.nlm.nih.gov/pubmed/22302147
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks003
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