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Stoichiometry of MutS and MutL at unrepaired mismatches in vivo suggests a mechanism of repair
Mismatch repair (MMR) is an evolutionarily conserved DNA repair system, which corrects mismatched bases arising during DNA replication. MutS recognizes and binds base pair mismatches, while the MutL protein interacts with MutS–mismatch complex and triggers MutH endonuclease activity at a distal-stra...
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| Main Authors: | , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Oxford University Press
2012
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3351158/ https://ncbi.nlm.nih.gov/pubmed/22241777 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkr1298 |
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