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Stoichiometry of MutS and MutL at unrepaired mismatches in vivo suggests a mechanism of repair

Mismatch repair (MMR) is an evolutionarily conserved DNA repair system, which corrects mismatched bases arising during DNA replication. MutS recognizes and binds base pair mismatches, while the MutL protein interacts with MutS–mismatch complex and triggers MutH endonuclease activity at a distal-stra...

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Detalhes bibliográficos
Main Authors: Elez, Marina, Radman, Miroslav, Matic, Ivan
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3351158/
https://ncbi.nlm.nih.gov/pubmed/22241777
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkr1298
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