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Matrilysin (MMP-7) Inhibition of BMP-7 Induced Renal Tubular Branching Morphogenesis Suggests a Role in the Pathogenesis of Human Renal Dysplasia

Congenital renal dysplasia (RD) is a severe form of congenital renal malformation characterized by disruption of normal renal development with cyst formation, reduced or absent nephrons, and impaired renal growth. The authors previously identified that matrilysin (matrix metalloproteinase–7) was ove...

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Detalhes bibliográficos
Main Authors: McGuire, John K., Harju-Baker, Susanna, Rims, Cliff, Sheen, Joong-Hyuk, Liapis, Helen
Formato: Artigo
Idioma:Inglês
Publicado em: SAGE Publications 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3351126/
https://ncbi.nlm.nih.gov/pubmed/22215634
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1369/0022155411435152
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