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Microcin C: biosynthesis and mechanisms of bacterial resistance

Nonhydrolyzable aminoacyl-adenylates that inhibit protein synthesis provide a promising route towards the development of novel antibiotics whose mechanism of action limits the appearance of bacterial drug resistance. The ‘Trojan horse’ antibiotic microcin C (McC) consists of a nonhydrolyzable aspart...

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Detalhes bibliográficos
Main Authors: Severinov, Konstantin, Nair, Satish K
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3350762/
https://ncbi.nlm.nih.gov/pubmed/22324995
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/fmb.11.148
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