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Microcin C: biosynthesis and mechanisms of bacterial resistance

Nonhydrolyzable aminoacyl-adenylates that inhibit protein synthesis provide a promising route towards the development of novel antibiotics whose mechanism of action limits the appearance of bacterial drug resistance. The ‘Trojan horse’ antibiotic microcin C (McC) consists of a nonhydrolyzable aspart...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Severinov, Konstantin, Nair, Satish K
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3350762/
https://ncbi.nlm.nih.gov/pubmed/22324995
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/fmb.11.148
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