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Systematic Discovery of Structural Elements Governing Mammalian mRNA Stability

Decoding post-transcriptional regulatory programs in RNA is a critical step in the larger goal to develop predictive dynamical models of cellular behavior. Despite recent efforts(1–3), the vast landscape of RNA regulatory elements remain largely uncharacterized. A longstanding obstacle is the contri...

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Hlavní autoři: Goodarzi, Hani, Najafabadi, Hamed S., Oikonomou, Panos, Greco, Todd M., Fish, Lisa, Salavati, Reza, Cristea, Ileana M., Tavazoie, Saeed
Médium: Artigo
Jazyk:Inglês
Vydáno: 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3350620/
https://ncbi.nlm.nih.gov/pubmed/22495308
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature11013
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