Aging Brain Microenvironment Decreases Hippocampal Neurogenesis Through Wnt-Mediated Survivin Signaling

Accumulating evidence suggests that adult hippocampus neurogenesis relies on the controlled and continued proliferation of neural progenitor cells (NPCs). With age, neurogenesis decreases through mechanisms that remain unclear, but are believed to involve changes in the NPC microenvironment. Here we...

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Autori principali: Miranda, Carlos J., Braun, Lyndsey, Jiang, Yuying, Hester, Mark E., Zhang, Ling, Riolo, Matthew, Wang, Haijuan, Rao, Meghan, Altura, Rachel A., Kaspar, Brian K.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2012
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3350615/
https://ncbi.nlm.nih.gov/pubmed/22404871
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1474-9726.2012.00816.x
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