Aging Brain Microenvironment Decreases Hippocampal Neurogenesis Through Wnt-Mediated Survivin Signaling

Accumulating evidence suggests that adult hippocampus neurogenesis relies on the controlled and continued proliferation of neural progenitor cells (NPCs). With age, neurogenesis decreases through mechanisms that remain unclear, but are believed to involve changes in the NPC microenvironment. Here we...

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Detalhes bibliográficos
Main Authors: Miranda, Carlos J., Braun, Lyndsey, Jiang, Yuying, Hester, Mark E., Zhang, Ling, Riolo, Matthew, Wang, Haijuan, Rao, Meghan, Altura, Rachel A., Kaspar, Brian K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3350615/
https://ncbi.nlm.nih.gov/pubmed/22404871
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1474-9726.2012.00816.x
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