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Fluvastatin suppresses native and recombinant human P2X(4) receptor function

Statins have both cholesterol lowering and anti-inflammatory activities, whether mechanisms underlying their activities are independent remains unclear. The ATP-gated P2X(4) receptor is a pro-inflammatory mediator. Here, we investigate the action of fluvastatin and other cholesterol depleting agents...

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Detalhes bibliográficos
Main Authors: Li, Jing, Fountain, Samuel J.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Netherlands 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3350586/
https://ncbi.nlm.nih.gov/pubmed/22222818
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11302-011-9289-9
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