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Fluvastatin suppresses native and recombinant human P2X(4) receptor function
Statins have both cholesterol lowering and anti-inflammatory activities, whether mechanisms underlying their activities are independent remains unclear. The ATP-gated P2X(4) receptor is a pro-inflammatory mediator. Here, we investigate the action of fluvastatin and other cholesterol depleting agents...
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| Main Authors: | , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
Springer Netherlands
2012
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3350586/ https://ncbi.nlm.nih.gov/pubmed/22222818 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11302-011-9289-9 |
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