The stromal factors SDF1α, sFRP1 and VEGFD induce dopaminergic neuron differentiation of human pluripotent stem cells

Human embryonic stem cell (hESC)-derived dopaminergic (DA) neurons hold potential for treating Parkinson’s disease (PD) through cell replacement therapy. Generation of DA neurons from hESCs has been achieved by co-culture with the stromal cell line PA6, a source of stromal cell-derived inducing acti...

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Main Authors: Schwartz, Catherine M., Tavakoli, Tahereh, Jamias, Charmaine, Park, Sung-Soo, Maudsley, Stuart, Martin, Bronwen, Phillips, Terry M., Yao, Pamela J., Itoh, Katsuhiko, Ma, Wu, Rao, Mahendra S., Arenas, Ernest, Mattson, Mark P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3350575/
https://ncbi.nlm.nih.gov/pubmed/22535492
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jnr.23064
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