Genetic polymorphisms in MMP 2, 9 and 3 genes modify lung cancer risk and survival

BACKGROUND: Matrix metalloproteases (MMPs) are proteolytic enzymes that contribute to all stages of tumour progression, including the later stages of invasion and metastasis. Genetic variants in the MMP genes may influence the biological function of these enzymes and change their role in carcinogene...

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Main Authors: González-Arriaga, Patricia, Pascual, Teresa, García-Alvarez, Arturo, Fernández-Somoano, Ana, López-Cima, M Felicitas, Tardón, Adonina
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2012
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3350430/
https://ncbi.nlm.nih.gov/pubmed/22455335
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-12-121
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