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Genetic polymorphisms in MMP 2, 9 and 3 genes modify lung cancer risk and survival

BACKGROUND: Matrix metalloproteases (MMPs) are proteolytic enzymes that contribute to all stages of tumour progression, including the later stages of invasion and metastasis. Genetic variants in the MMP genes may influence the biological function of these enzymes and change their role in carcinogene...

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Detalhes bibliográficos
Main Authors: González-Arriaga, Patricia, Pascual, Teresa, García-Alvarez, Arturo, Fernández-Somoano, Ana, López-Cima, M Felicitas, Tardón, Adonina
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3350430/
https://ncbi.nlm.nih.gov/pubmed/22455335
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-12-121
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