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Development by environment interactions controlling tryptophan hydroxylase expression

Tryptophan hydroxylase is the rate-limiting enzyme in the biosynthesis of serotonin (5-hydroxytryptamine; 5-HT). Two isoforms of tryptophan hydroxylase, derived from different genes, tph1 and tph2, have been identified. The tph1 isoform is expressed in peripheral tissues, whereas tph2 is brain and n...

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Main Authors: Hale, Matthew W., Shekhar, Anantha, Lowry, Christopher A.
格式: Artigo
語言:Inglês
出版: 2011
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3350375/
https://ncbi.nlm.nih.gov/pubmed/21640184
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jchemneu.2011.05.002
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