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Development by environment interactions controlling tryptophan hydroxylase expression

Tryptophan hydroxylase is the rate-limiting enzyme in the biosynthesis of serotonin (5-hydroxytryptamine; 5-HT). Two isoforms of tryptophan hydroxylase, derived from different genes, tph1 and tph2, have been identified. The tph1 isoform is expressed in peripheral tissues, whereas tph2 is brain and n...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Hale, Matthew W., Shekhar, Anantha, Lowry, Christopher A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3350375/
https://ncbi.nlm.nih.gov/pubmed/21640184
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jchemneu.2011.05.002
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