The Role of Apelin on the Alleviative Effect of Angiotensin Receptor Blocker in Unilateral Ureteral Obstruction-Induced Renal Fibrosis

BACKGROUND: Apelin is a selective endogenous ligand of the APJ receptor, which genetically has closest identity to the angiotensin II type 1 receptor (AT-1). The effects of the apelin/APJ system on renal fibrosis still remain unclear. METHODS: We examined the effects of the apelin/APJ system on rena...

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Autors principals: Nishida, Masashi, Okumura, Yasuko, Oka, Tatsujiro, Toiyama, Kentaro, Ozawa, Seiichiro, Itoi, Toshiyuki, Hamaoka, Kenji
Format: Artigo
Idioma:Inglês
Publicat: S. Karger AG 2012
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Original Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3350347/
https://ncbi.nlm.nih.gov/pubmed/22619666
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000337091
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