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An Engineered Lantibiotic Synthetase That Does Not Require a Leader Peptide on Its Substrate

[Image: see text] Ribosomally synthesized and post-translationally modified peptides are a rapidly expanding class of natural products. They are typically biosynthesized by modification of a C-terminal segment of the precursor peptide (the core peptide). The precursor peptide also contains an N-term...

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Autors principals: Oman, Trent J., Knerr, Patrick J., Bindman, Noah A., Velásquez, Juan E., van der Donk, Wilfred A.
Format: Artigo
Idioma:Inglês
Publicat: American Chemical Society 2012
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3350211/
https://ncbi.nlm.nih.gov/pubmed/22480178
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja3017297
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