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In vitro preferential topoisomerization of bent DNA.
The steps of the topoisomerization reaction by calf thymus DNA topoisomerase I on a DNA domain containing an intrinsically bent DNA sequence have been analyzed. High preferentiality of binding, cleavage and topoisomerization on the bent segment relative to the rest of the DNA domain was observed. Th...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
1989
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| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC335019/ https://ncbi.nlm.nih.gov/pubmed/2555772 |
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