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Attacking a Nexus of the Oncogenic Circuitry by Reversing Aberrant eIF4F-Mediated Translation

Notwithstanding their genetic complexity, different cancers share a core group of perturbed pathways converging upon a few regulatory nodes that link the intracellular signaling network with the basic metabolic machinery. The clear implication of this view for cancer therapy is that instead of targe...

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Detalhes bibliográficos
Main Authors: Bitterman, Peter B., Polunovsky, Vitaly A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3349966/
https://ncbi.nlm.nih.gov/pubmed/22572598
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-11-0530
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