A high concentration of genistein down-regulates activin A, Smad3 and other TGF-β pathway genes in human uterine leiomyoma cells

Previously, we found that high doses of genistein show an inhibitory effect on uterine leiomyoma (UtLM) cell proliferation. In this study, using microarray analysis and Ingenuity Pathways Analysis™, we identified genes (up- or down-regulated, ≥ 1.5 fold, P ≤ 0.001), functions and signaling pathways...

Description complète

Enregistré dans:
Détails bibliographiques
Auteurs principaux: Di, Xudong, Andrews, Danica M.K., Tucker, Charles J., Yu, Linda, Moore, Alicia B., Zheng, Xiaolin, Castro, Lysandra, Hermon, Tonia, Xiao, Hang, Dixon, Darlene
Format: Artigo
Langue:Inglês
Publié: Korean Society for Biochemistry and Molecular Biology 2012
Sujets:
Original Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3349910/
https://ncbi.nlm.nih.gov/pubmed/22228119
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3858/emm.2012.44.4.024
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires