β1 Integrin Gene Excision in the Adult Murine Cardiac Myocyte Causes Defective Mechanical and Signaling Responses

How mechanical signals are transmitted in the cardiac myocyte is poorly understood. In this study, we produced a tamoxifen-inducible mouse model in which β1 integrin could be reduced specifically in the adult cardiomyocyte, so that the function of this integrin could be assessed in the postnatal and...

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Detalhes bibliográficos
Main Authors: Li, Ruixia, Wu, Ying, Manso, Ana Maria, Gu, Yusu, Liao, Peter, Israeli, Sharon, Yajima, Toshitaka, Nguyen, Uyen, Huang, Michael S., Dalton, Nancy D., Peterson, Kirk L., Ross, Robert S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2012
Assuntos:
Regular Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3349893/
https://ncbi.nlm.nih.gov/pubmed/22248583
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2011.12.007
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