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Filament Compliance Influences Cooperative Activation of Thin Filaments and the Dynamics of Force Production in Skeletal Muscle
Striated muscle contraction is a highly cooperative process initiated by Ca(2+) binding to the troponin complex, which leads to tropomyosin movement and myosin cross-bridge (XB) formation along thin filaments. Experimental and computational studies suggest skeletal muscle fiber activation is greatly...
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| Autori principali: | , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Public Library of Science
2012
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3349719/ https://ncbi.nlm.nih.gov/pubmed/22589710 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1002506 |
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