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Distinct RGK GTPases Differentially Use α(1)- and Auxiliary β-Binding-Dependent Mechanisms to Inhibit Ca(V)1.2/Ca(V)2.2 Channels
Ca(V)1/Ca(V)2 channels, comprised of pore-forming α(1) and auxiliary (β,α(2)δ) subunits, control diverse biological responses in excitable cells. Molecules blocking Ca(V)1/Ca(V)2 channel currents (I (Ca)) profoundly regulate physiology and have many therapeutic applications. Rad/Rem/Rem2/Gem GTPases...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3349659/ https://ncbi.nlm.nih.gov/pubmed/22590648 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0037079 |
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