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cGMP-Phosphodiesterase Inhibition Enhances Photic Responses and Synchronization of the Biological Circadian Clock in Rodents

The master circadian clock in mammals is located in the hypothalamic suprachiasmatic nuclei (SCN) and is synchronized by several environmental stimuli, mainly the light-dark (LD) cycle. Light pulses in the late subjective night induce phase advances in locomotor circadian rhythms and the expression...

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Detalhes bibliográficos
Main Authors: Plano, Santiago A., Agostino, Patricia V., de la Iglesia, Horacio O., Golombek, Diego A.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3349644/
https://ncbi.nlm.nih.gov/pubmed/22590651
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0037121
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