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Detection of minority point mutations by modified PCR technique: a new approach for a sensitive diagnosis of tumor-progression markers.

The detection of point mutations correlated with diseases, in enzymatically amplified DNA sequences (Polymerase Chain Reaction), is currently performed by digestion of PCR products when an existing restriction site disappears at least in one allele of the amplified mutated sequence or by allele spec...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Haliassos, A, Chomel, J C, Grandjouan, S, Kruh, J, Kaplan, J C, Kitzis, A
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 1989
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC334949/
https://ncbi.nlm.nih.gov/pubmed/2573037
Tagiau: Ychwanegu Tag
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