Allergic inflammation induces a persistent mechanistic switch in thromboxane-mediated airway constriction in the mouse

Actions of thromboxane (TXA(2)) to alter airway resistance were first identified over 25 years ago. However, the mechanism underlying this physiological response has remained largely undefined. Here we address this question using a novel panel of mice in which expression of the thromboxane receptor...

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Bibliographic Details
Main Authors: Cyphert, Jaime M., Allen, Irving C., Church, Rachel J., Latour, Anne M., Snouwaert, John N., Coffman, Thomas M., Koller, Beverly H.
Format: Artigo
Language:Inglês
Published: American Physiological Society 2012
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Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3349367/
https://ncbi.nlm.nih.gov/pubmed/21984570
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00152.2011
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