PPARγ agonists regulate the expression of stemness and differentiation genes in brain tumour stem cells

BACKGROUND: Brain tumour stem cells (BTSCs) are a small population of cancer cells that exhibit self-renewal, multi-drug resistance, and recurrence properties. We have shown earlier that peroxisome proliferator-activated receptor gamma (PPARγ) agonists inhibit the expansion of BTSCs in T98G and U87M...

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Detalhes bibliográficos
Main Authors: Pestereva, E, Kanakasabai, S, Bright, J J
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2012
Assuntos:
Genetics and Genomics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3349185/
https://ncbi.nlm.nih.gov/pubmed/22531638
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2012.161
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