Differential effects of aprotinin and tranexamic acid on outcomes and cytokine profiles in neonates undergoing cardiac surgery

OBJECTIVE: Factors contributing to postoperative complications include blood loss and a heightened inflammatory response. The objective of this study was to test the hypothesis that aprotinin would decrease perioperative blood product use, reduce biomarkers of inflammation, and result in improved cl...

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Main Authors: Graham, Eric M., Atz, Andrew M., Gillis, Jenna, DeSantis, Stacia M., Haney, A. Lauren, Deardorff, Rachael L., Uber, Walter E., Reeves, Scott T., McGowan, Francis X., Bradley, Scott M., Spinale, Francis G.
Format: Artigo
Sprog:Inglês
Udgivet: 2011
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3349086/
https://ncbi.nlm.nih.gov/pubmed/22075061
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jtcvs.2011.08.051
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