A Genome-Wide siRNA Screen to Identify Modulators of Insulin Sensitivity and Gluconeogenesis

BACKGROUND: Hepatic insulin resistance impairs insulin’s ability to suppress hepatic glucose production (HGP) and contributes to the development of type 2 diabetes (T2D). Although the interests to discover novel genes that modulate insulin sensitivity and HGP are high, it remains challenging to have...

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Detalhes bibliográficos
Main Authors: Yang, Ruojing, Lacson, Raul G., Castriota, Gino, Zhang, Xiaohua D., Liu, Yaping, Zhao, Wenqing, Einstein, Monica, Camargo, Luiz Miguel, Qureshi, Sajjad, Wong, Kenny K., Zhang, Bei B., Ferrer, Marc, Berger, Joel P.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3348929/
https://ncbi.nlm.nih.gov/pubmed/22590537
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0036384
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