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P190B RhoGAP Regulates Chromosome Segregation in Cancer Cells

Rho GTPases are overexpressed and hyperactivated in many cancers, including breast cancer. Rho proteins, as well as their regulators and effectors, have been implicated in mitosis, and their altered expression promotes mitotic defects and aneuploidy. Previously, we demonstrated that p190B Rho GTPase...

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Detaylı Bibliyografya
Asıl Yazarlar: Hwang, Melissa, Peddibhotla, Sirisha, McHenry, Peter, Chang, Peggy, Yochum, Zachary, Park, Ko Un, Sears, James Cooper, Vargo-Gogola, Tracy
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: MDPI 2012
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3348653/
https://ncbi.nlm.nih.gov/pubmed/22582143
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers4020475
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