Haploinsufficiency for p190B RhoGAP inhibits MMTV-Neu tumor progression

INTRODUCTION: Rho signaling regulates key cellular processes including proliferation, survival, and migration, and it has been implicated in the development of many types of cancer including breast cancer. P190B Rho GTPase activating protein (RhoGAP) functions as a major inhibitor of the Rho GTPases...

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Autores principales: Heckman-Stoddard, Brandy M, Vargo-Gogola, Tracy, McHenry, Peter R, Jiang, Vivian, Herrick, Matthew P, Hilsenbeck, Susan G, Settleman, Jeffrey, Rosen, Jeffrey M
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2009
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2750123/
https://ncbi.nlm.nih.gov/pubmed/19703301
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/bcr2352
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