Haploinsufficiency for p190B RhoGAP inhibits MMTV-Neu tumor progression

INTRODUCTION: Rho signaling regulates key cellular processes including proliferation, survival, and migration, and it has been implicated in the development of many types of cancer including breast cancer. P190B Rho GTPase activating protein (RhoGAP) functions as a major inhibitor of the Rho GTPases...

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主要な著者: Heckman-Stoddard, Brandy M, Vargo-Gogola, Tracy, McHenry, Peter R, Jiang, Vivian, Herrick, Matthew P, Hilsenbeck, Susan G, Settleman, Jeffrey, Rosen, Jeffrey M
フォーマット: Artigo
言語:Inglês
出版事項: BioMed Central 2009
主題:
Research Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2750123/
https://ncbi.nlm.nih.gov/pubmed/19703301
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/bcr2352
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