Haploinsufficiency for p190B RhoGAP inhibits MMTV-Neu tumor progression

INTRODUCTION: Rho signaling regulates key cellular processes including proliferation, survival, and migration, and it has been implicated in the development of many types of cancer including breast cancer. P190B Rho GTPase activating protein (RhoGAP) functions as a major inhibitor of the Rho GTPases...

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Detalhes bibliográficos
Main Authors: Heckman-Stoddard, Brandy M, Vargo-Gogola, Tracy, McHenry, Peter R, Jiang, Vivian, Herrick, Matthew P, Hilsenbeck, Susan G, Settleman, Jeffrey, Rosen, Jeffrey M
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2009
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2750123/
https://ncbi.nlm.nih.gov/pubmed/19703301
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/bcr2352
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