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P190B RhoGAP Regulates Chromosome Segregation in Cancer Cells
Rho GTPases are overexpressed and hyperactivated in many cancers, including breast cancer. Rho proteins, as well as their regulators and effectors, have been implicated in mitosis, and their altered expression promotes mitotic defects and aneuploidy. Previously, we demonstrated that p190B Rho GTPase...
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| Главные авторы: | , , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
MDPI
2012
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3348653/ https://ncbi.nlm.nih.gov/pubmed/22582143 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers4020475 |
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