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P190B RhoGAP Regulates Chromosome Segregation in Cancer Cells

Rho GTPases are overexpressed and hyperactivated in many cancers, including breast cancer. Rho proteins, as well as their regulators and effectors, have been implicated in mitosis, and their altered expression promotes mitotic defects and aneuploidy. Previously, we demonstrated that p190B Rho GTPase...

詳細記述

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書誌詳細
主要な著者: Hwang, Melissa, Peddibhotla, Sirisha, McHenry, Peter, Chang, Peggy, Yochum, Zachary, Park, Ko Un, Sears, James Cooper, Vargo-Gogola, Tracy
フォーマット: Artigo
言語:Inglês
出版事項: MDPI 2012
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3348653/
https://ncbi.nlm.nih.gov/pubmed/22582143
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers4020475
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