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P190B RhoGAP Regulates Chromosome Segregation in Cancer Cells

Rho GTPases are overexpressed and hyperactivated in many cancers, including breast cancer. Rho proteins, as well as their regulators and effectors, have been implicated in mitosis, and their altered expression promotes mitotic defects and aneuploidy. Previously, we demonstrated that p190B Rho GTPase...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Hwang, Melissa, Peddibhotla, Sirisha, McHenry, Peter, Chang, Peggy, Yochum, Zachary, Park, Ko Un, Sears, James Cooper, Vargo-Gogola, Tracy
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: MDPI 2012
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3348653/
https://ncbi.nlm.nih.gov/pubmed/22582143
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers4020475
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