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P190B RhoGAP Regulates Chromosome Segregation in Cancer Cells

Rho GTPases are overexpressed and hyperactivated in many cancers, including breast cancer. Rho proteins, as well as their regulators and effectors, have been implicated in mitosis, and their altered expression promotes mitotic defects and aneuploidy. Previously, we demonstrated that p190B Rho GTPase...

وصف كامل

محفوظ في:
التفاصيل البيبلوغرافية
المؤلفون الرئيسيون: Hwang, Melissa, Peddibhotla, Sirisha, McHenry, Peter, Chang, Peggy, Yochum, Zachary, Park, Ko Un, Sears, James Cooper, Vargo-Gogola, Tracy
التنسيق: Artigo
اللغة:Inglês
منشور في: MDPI 2012
الموضوعات:
الوصول للمادة أونلاين:https://ncbi.nlm.nih.gov/pmc/articles/PMC3348653/
https://ncbi.nlm.nih.gov/pubmed/22582143
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers4020475
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