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Kv4.2 knockout mice have hippocampal-dependent learning and memory deficits
Kv4.2 channels contribute to the transient, outward K(+) current (A-type current) in hippocampal dendrites, and modulation of this current substantially alters dendritic excitability. Using Kv4.2 knockout (KO) mice, we examined the role of Kv4.2 in hippocampal-dependent learning and memory. We found...
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| Main Authors: | , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Cold Spring Harbor Laboratory Press
2012
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3348517/ https://ncbi.nlm.nih.gov/pubmed/22505720 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/lm.023614.111 |
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