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dSir2 deficiency in the fatbody, but not muscles, affects systemic insulin signaling, fat mobilization and starvation survival in flies

Sir2 is an evolutionarily conserved NAD(+) dependent protein. Although, SIRT1 has been implicated to be a key regulator of fat and glucose metabolism in mammals, the role of Sir2 in regulating organismal physiology, in invertebrates, is unclear. Drosophila has been used to study evolutionarily conse...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Banerjee, Kushal Kr., Ayyub, Champakali, Sengupta, Samudra, Kolthur-Seetharam, Ullas
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: Impact Journals LLC 2012
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3348481/
https://ncbi.nlm.nih.gov/pubmed/22411915
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