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Cell cycle arrest is not yet senescence, which is not just cell cycle arrest: terminology for TOR-driven aging

Cell cycle arrest is not yet senescence. When the cell cycle is arrested, an inappropriate growth-promotion converts an arrest into senescence (geroconversion). By inhibiting the growth-promoting mTOR pathway, rapamycin decelerates geroconversion of the arrested cells. And as a striking example, whi...

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Hlavní autor: Blagosklonny, Mikhail V.
Médium: Artigo
Jazyk:Inglês
Vydáno: Impact Journals LLC 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3348476/
https://ncbi.nlm.nih.gov/pubmed/22394614
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