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LIPID RAFTS AND FUNCTIONAL CAVEOLAE REGULATE HIV-INDUCED AMYLOID BETA ACCUMULATION IN BRAIN ENDOTHELIAL CELLS
Amyloid beta (Aβ) levels are increased in HIV-1 infected brains due to not yet fully understood mechanisms. In the present study, we investigate the role of lipid rafts, functional caveolae, and caveolae-associated signaling in HIV-1-induced Aβ accumulation in HBMEC. Both silencing of caveolin-1 (ca...
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| Autores principales: | , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2012
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3348457/ https://ncbi.nlm.nih.gov/pubmed/22490665 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2012.03.128 |
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