Genomic and Clinical Analysis of Fusion Gene Amplification in Rhabdomyosarcoma: a Report from the Children’s Oncology Group

Alveolar rhabdomyosarcoma is an aggressive pediatric cancer of the myogenic lineage with frequent chromosomal translocations involving the PAX3 or PAX7 and FOXO1 genes. Based on previous studies indicating that the fusion genes are amplified in a subset of these cancers, we conducted a comprehensive...

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Main Authors: Duan, Fenghai, Smith, Lynette M., Gustafson, Donna M., Zhang, Chune, Dunlevy, Mandy J., Gastier-Foster, Julie M., Barr, Frederic G.
Format: Artigo
Jezik:Inglês
Izdano: 2012
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3348443/
https://ncbi.nlm.nih.gov/pubmed/22447499
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/gcc.21953
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