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Genomic and clinical analysis of amplification of the 13q31 chromosomal region in alveolar rhabdomyosarcoma: a report from the Children’s Oncology Group

PURPOSE: This study determined the molecular characteristics and clinical significance of amplification of the 13q31 chromosomal region in alveolar rhabdomyosarcoma (ARMS), an aggressive pediatric cancer with frequent PAX3-FOXO1 and PAX7-FOXO1 gene fusions. EXPERIMENTAL DESIGN: The 13q31 amplicon wa...

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Bibliografiset tiedot
Päätekijät: Reichek, Jennifer L., Duan, Fenghai, Smith, Lynette M., Gustafson, Donna M., O’Connor, Roddy S., Zhang, Chune, Pitts, Mandy J., Gastier-Foster, Julie M., Barr, Frederic G.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2011
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Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3060277/
https://ncbi.nlm.nih.gov/pubmed/21220470
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-10-0091
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