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Pathogen-specific T cell depletion and reactivation of opportunistic pathogens in HIV infection

During HIV infection, it is unclear why different opportunistic pathogens cause disease at different CD4 T cell count thresholds. Early work showed that CD4 T cell depletion is influenced both by cellular activation status and expression of viral entry receptors. More recently, functional characteri...

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Bibliografiske detaljer
Main Authors: Geldmacher, Christof, Koup, Richard A.
Format: Artigo
Sprog:Inglês
Udgivet: 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3348406/
https://ncbi.nlm.nih.gov/pubmed/22398371
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.it.2012.01.011
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