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Differential Effects of Procaspase-3 Activating Compounds in the Induction of Cancer Cell Death

The evasion of apoptosis is a key characteristic of cancer, and thus strategies to selectively induce apoptosis in cancer cells hold considerable promise in personalized anticancer therapy. Structurally similar procaspase activating compounds PAC-1 and S-PAC-1 restore procaspase-3 activity through t...

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Detalhes bibliográficos
Main Authors: West, Diana C., Qin, Yan, Peterson, Quinn P., Thomas, Diana L, Palchaudhuri, Rahul, Morrison, Karen C., Lucas, Pamela W., Palmer, Amy E., Fan, Timothy M., Hergenrother, Paul J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3348238/
https://ncbi.nlm.nih.gov/pubmed/22486564
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/mp200673n
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