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Integrated Analysis of Residue Coevolution and Protein Structure in ABC Transporters
Intraprotein side chain contacts can couple the evolutionary process of amino acid substitution at one position to that at another. This coupling, known as residue coevolution, may vary in strength. Conserved contacts thus not only define 3-dimensional protein structure, but also indicate which resi...
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2012
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3348156/ https://ncbi.nlm.nih.gov/pubmed/22590562 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0036546 |
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