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Prion-like spread of protein aggregates in neurodegeneration

Protein misfolding is common to most neurodegenerative diseases, including Alzheimer’s and Parkinson’s diseases. Recent work using animal models with intracellular α-synuclein and tau inclusions adds decisively to a growing body of evidence that misfolded protein aggregates can induce a self-perpetu...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Polymenidou, Magdalini, Cleveland, Don W.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: The Rockefeller University Press 2012
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3348110/
https://ncbi.nlm.nih.gov/pubmed/22566400
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20120741
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