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Prion-like spread of protein aggregates in neurodegeneration
Protein misfolding is common to most neurodegenerative diseases, including Alzheimer’s and Parkinson’s diseases. Recent work using animal models with intracellular α-synuclein and tau inclusions adds decisively to a growing body of evidence that misfolded protein aggregates can induce a self-perpetu...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
The Rockefeller University Press
2012
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3348110/ https://ncbi.nlm.nih.gov/pubmed/22566400 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20120741 |
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