Transcriptional trans-repression by the c-myb proto-oncogene product.

We report that the c-myb protein binds to another site, MBS-II, in the SV40 enhancer with low affinity. In co-transfection experiments with a c-myb expression plasmid, tandem repeats of the sequence containing the MBS-II site induced c-myb-dependent transcriptional repression. Results of mutational...

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Bibliografiske detaljer
Main Authors: Nakagoshi, H, Nagase, T, Ueno, Y, Ishii, S
Format: Artigo
Sprog:Inglês
Udgivet: 1989
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC334811/
https://ncbi.nlm.nih.gov/pubmed/2552408
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